Unraveling Plant Natural Chemical Diversity for Drug Discovery Purposes
نویسندگان
چکیده
منابع مشابه
ChemGAN challenge for drug discovery: can AI reproduce natural chemical diversity?
Generating molecules with desired chemical properties is important for drug discovery. The use of generative neural networks is promising for this task. However, from visual inspection, it often appears that generated samples lack diversity. In this paper, we quantify internal chemical diversity, and we raise the following challenge: can a nontrivial AI model reproduce natural chemical diversit...
متن کاملmechanisms for discovery purposes sharia
ways to aggression the text, check the sentences causality and the criteria and mechanisms for discovery purposes sharia, sharia dynamic the discursive, that could change latest and changes in situations and social conditions, to determine how changes in sentences. however, nderstanding ends of sentences, although caused development of the jurisprudence, but it can not be without regulation. pr...
متن کاملNatural cannabinoids: templates for drug discovery.
Recent studies have elucidated the biosynthetic pathway of cannabinoids and have highlighted the preference for a C-3 n-pentyl side chain in the most prominently represented cannabinoids from Cannabis sativa and their medicinally important decarboxylation products. The corresponding C-3 n-propyl side chain containing cannabinoids are also found, although in lesser quantities. Structure-activity...
متن کاملUnconventional natural sources for future drug discovery.
Natural products used as food or drinks, clues from the fascinating science of zoopharmacognosy, terrestrial animals and their excreta, and many other NPs not primarily known for their medical use, seem to have, to a great extent, escaped the attention of natural product research. It is nevertheless highly probable that these sources could contain biologically active compounds, some of which wi...
متن کاملGuiding principles for natural product drug discovery.
Natural products (NPs) have historically been a fertile source of new drugs for the pharmaceutical industry. However, this once-popular approach has waned considerably over the past two decades as the high-throughput screening of megalibraries comprised mainly of molecules with non-natural (synthetic) motifs has unfolded. Contemporary high-throughput screening libraries contain molecules compli...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2020
ISSN: 1663-9812
DOI: 10.3389/fphar.2020.00397